業績紹介

神経再生医療学部門の業績の紹介です。
  • Shinichi Oka , Tomohiro Yamaki, Masanori Sasaki, Ryo Ukai , Mitsuhiro Takemura , Takahiro Yokoyama , Yuko Kataoka-Sasaki, Rie Onodera , Yoichi M Ito , Shigeki Kobayashi , Jeffery D Kocsis , Yasuo Iwadate , Osamu Honmou Intravenous Infusion of Autoserum-Expanded Autologous Mesenchymal Stem Cells in Patients With Chronic Brain Injury: Protocol for a Phase 2 Trial JMIR Res Protoc. 2022 Jul 6;11(7):e37898.
  • Mari Maeda-Yamamoto , Osamu Honmou , Masanori Sasaki , Akane Haseda , Hiroyo Kagami-Katsuyama , Toshihiko Shoji , Ai Namioka , Takahiro Namioka , Hirotoshi Magota , Shinichi Oka , Yuko Kataoka-Sasaki , Ryou Ukai , Mitsuhiro Takemura , Jun Nishihira The Impact of Purple-Flesh Potato ( Solanum tuberosum L.) cv. "Shadow Queen" on Minor Health Complaints in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study Nutrients. 2022 Jun 13;14(12):2446.
  • Ryosuke Hirota, Masanori Sasaki, Yuko Kataoka-Sasaki, Tsutomu Oshigiri, Kota Kurihara, Ryunosuke Fukushi, Shinichi Oka, Ryo Ukai, Mitsunori Yoshimoto, Jeffery D Kocsis, Toshihiko Yamashita, Osamu Honmou Enhanced network in corticospinal tracts after infused mesenchymal stem cells in spinal cord injury J Neurotrauma. 2022 May 25.
  • Masahito Nakazaki, Shinichi Oka, Hirotoshi Magota, Ryo Kiyose, Rie Onodera, Ryo Ukai, Yuko Kataoka-Sasaki, Masanori Sasaki, Osamu Honmou Pharmacological Difference Between Platelet Aggregations in Cardioembolic Stroke Patients with Direct Oral Anticoagulants: A Pilot Study J Stroke Cerebrovasc Dis. 2022 May 3;31(7):106520
  • Mitsuhiro Takemura, Masanori Sasaki, Yuko Kataoka-Sasaki, Ryo Kiyose, Hiroshi Nagahama, Shinichi Oka, Ryo Ukai, Takahiro Yokoyama, Jeffery D. Kocsis, Tetsuya Ueba, Osamu Honmou Repeated intravenous infusion of mesenchymal stem cells for enhanced functional recovery in a rat model of chronic cerebral ischemia J Neurosurg. 2021 Dec 3;1-10.
  • Hidetoshi Tabata, Masanori Sasaki, Yuko Kataoka-Sasaki, Nobuo Shinkai, Koji Ichihara, Naoya Masumori, Jeffery D. Kocsis, Osamu Honmou Possible role of intravenous administration of mesenchymal stem cells to alleviate interstitial cystitis/bladder pain syndrome in a Toll-like receptor-7 agonist-induced experimental animal model in rat BMC Urol. 2021 Nov 13;21(1):156.
  • Tsugufumi Nakagawa, Masanori Sasaki, Yuko Kataoka-Sasaki, Takatoshi Yotsuyanagi, Christine Radtke, Jeffery D. Kocsis, Osamu Honmou Intravenous Infusion of Mesenchymal Stem Cells Promotes the Survival of Random Pattern Flaps in Rats Plast Reconstr Surg. 2021 Oct 1;148(4):799-807.
  • Hirotoshi Magota, Masanori Sasaki, Yuko Kataoka-Sasaki, Shinichi Oka, Ryo Ukai, Ryo Kiyose, Rie Onodera, Jeffery D Kocsis, Osamu Honmou Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis Mol Brain. 2021 May 7;14(1):76.
  • Honmou O, Yamashita T, Morita T, Oshigiri T, Hirota R, Iyama S, Kato J, Sasaki Y, Ishiai S, Ito YM, Namioka A, Namioka T, Nakazaki M, Kataoka-Sasaki Y, Onodera R, Oka S, Sasaki M, Waxman SG, Kocsis JD. Intravenous infusion of auto serum-expanded autologous mesenchymal stem cells in spinal cord injury patients: 13 case series. Clin Neurol Neurosurg. 2021 Apr;203:106565.
  • Ryo Kiyose, Masanori Sasaki, Yuko Kataoka-Sasaki, Masahito Nakazaki, Hiroshi Nagahama, Hirotoshi Magota, Shinichi Oka, Ryo Ukai, Mitsuhiro Takemura, Takahiro Yokoyama, Jeffery D Kocsis, Osamu Honmou Intravenous infusion of mesenchymal stem cells enhances therapeutic efficacy of reperfusion therapy in cerebral ischemia World Neurosurg. 2021 Feb 19;S1878-8750
  • Ai Namioka, Takahiro Namioka, Masanori Sasaki, Jeffery D Kocsis, Osamu Honmou Focal brainstem infarction in the adult rat Lab Anim (NY) 2021 Feb 9
  • Hirotoshi Magota, Masanori Sasaki, Yuko Kataoka-Sasaki, Shinichi Oka, Ryo Ukai, Ryo Kiyose, Rie Onodera, Jeffery D Kocsis, Osamu Honmou Intravenous infusion of mesenchymal stem cells delays disease progression in the SOD1G93A transgenic amyotrophic lateral sclerosis rat model Brain Res 2021 Jan 28;147296.
  • Masahito Nakazaki, Shinichi Oka, Masanori Sasaki, Yuko Kataoka-Sasaki, Hiroshi Nagahama, Kazuo Hashi, Jeffery D Kocsis, Osamu Honmou Prolonged lifespan in a spontaneously hypertensive rat (stroke prone) model following intravenous infusion of mesenchymal stem cells Heliyon 2020 Dec 25;6(12)
  • Yasuda N, Sasaki M, Kataoka-Sasaki Y, Nagahama H, Kocsis JD, Kawaharada N, Honmou O. Intravenous delivery of mesenchymal stem cells protects both white and gray matter in spinal cord ischemia. Brain Res. 2020 Aug 6;1747:147040.
  • Sasaki M, Oka S, Kataoka-Sasaki Y, Kocsis JD, Honmou O. "Chronic" State in Neural Diseases as the Target of Cellular Therapy with Mesenchymal Stem Cells. World Neurosurg. 2020 Mar;135:375-376.
  • Nakazaki M, Oka S, Sasaki M, Kataoka-Sasaki Y, Onodera R, Komatsu K, Iihoshi S, Hiroura M, Kawaguchi A, Kocsis JD, Honmou O. Prevention of neointimal hyperplasia induced by an endovascular stent via intravenousinfusion of mesenchymal J Neurosurg. 2019 Oct 4:1-13.
  • Nakazaki M, Sasaki M, Kataoka-Sasaki Y, Oka S, Suzuki J, Sasaki Y, Nagahama H, Hashi K, Kocsis JD, Honmou O. Intravenous infusion of mesenchymal stem cells improves impaired cognitive function in a cerebral small vessel disease model. Neuroscience. 2019 Apr 16. pii: S0306-4522(19)30258-1. doi: 10.1016/j.neuroscience.2019.04.018.
  • Namioka A, Namioka T, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Onodera R, Suzuki J, Sasaki Y, Nagahama H, Kocsis JD, Honmou O. Intravenous infusion of mesenchymal stem cells for protection against brainstem infarction in a persistent basilar artery occlusion model in the adult rat. J Neurosurg. 2018 Oct 1:1-9.
  • Namioka T, Namioka A, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Onodera R, Suzuki J, Sasaki Y, Nagahama H, Kocsis JD, Honmou O. Intravenous infusion of mesenchymal stem cells promotes functional recovery in a rat model of chronic cerebral infarction. J Neurosurg. 2018 Oct 1:1-8.
  • Sakai T, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Fukumura S, Kobayashi M, Tsutsumi H, Kocsis JD, Honmou O. Functional recovery after the systemic administration of mesenchymal stem cells in a rat model of neonatal hypoxia-ischemia. J Neurosurg Pediatr. 2018 Aug 3:1-10.
  • Wanibuchi M, Ohtaki S, Ookawa S, Kataoka-Sasaki Y, Sasaki M, Oka S, Kimura Y, Akiyama Y, Mikami T, Mikuni N, Kocsis JD, Honmou O. Actin, alpha, cardiac muscle 1 (ACTC1) knockdown inhibits the migration of glioblastoma cells in vitro. J Neurol Sci. 2018 Jul 17;392:117-121.
  • Oshigiri T, Sasaki T, Sasaki M, Kataoka-Sasaki Y, Nakazaki M, Oka S, Morita T, Hirota R, Yoshimoto M, Yamashita T, Hashimoto-Torii K, Honmou O. Intravenous Infusion of Mesenchymal Stem Cells Alters Motor Cortex Gene Expression in a Rat Model of Acute Spinal Cord Injury. J Neurotrauma. 2018 Jun 14.
  • Nagahama H, Nakazaki M, Sasaki M, Kataoka-Sasaki Y, Namioka T, Namioka A, Oka S, Onodera R, Suzuki J, Sasaki Y, Kocsis JD, Honmou O. Preservation of interhemispheric cortical connections through corpus callosum following intravenous infusion of mesenchymal stem cells in a rat model of cerebral infarction. Brain Res. 2018 Sep 15;1695:37-44.
  • Houkin K, Shichinohe H, Abe K, Arato T, Dezawa M, Honmou O, Horie N, Katayama Y, Kudo K, Kuroda S, Matsuyama T, Miyai I, Nagata I, Niizuma K, Sakushima K, Sasaki M, Sato N, Sawanobori K, Suda S, Taguchi A, Tominaga T, Yamamoto H, Yamashita T, Yoshimine T; Working Group for Guidelines on Development of Cell-Based Products for the Treatment of Cerebral Infarction. Accelerating Cell Therapy for Stroke in Japan: Regulatory Framework and Guidelines on Development of Cell-Based Products. Stroke. 2018 Apr;49(4):e145-e152.
  • Fukumura S, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Nagahama H, Morita T, Sakai T, Tsutsumi H, Kocsis JD, Honmou O. Intravenous infusion of mesenchymal stem cells reduces epileptogenesis in a rat model of status epilepticus. Epilepsy Res. 2018 Mar;141:56-63.
  • Ookawa S, Wanibuchi M, Kataoka-Sasaki Y, Sasaki M, Oka S, Ohtaki S, Noshiro S, Komatsu K, Akiyama Y, Mikami T, Mikuni N, Kocsis JD, Honmou O. Digital Polymerase Chain Reaction Quantification of SERPINA1 Predicts Prognosis in High-Grade Glioma. World Neurosurg. 2018 Mar;111:e783-e789.
  • Matsuda Y, Sasaki M, Kataoka-Sasaki Y, Takayanagi A, Kobayashi K, Oka S, Nakazaki M, Masumori N, Kocsis JD, Honmou O. Intravenous Infusion of Bone Marrow-Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats. Sex Med. 2018 Mar;6(1):49-57.
  • Nakazaki M, Nonaka T, Nomura T, Onda T, Yonemasu Y, Takahashi A, Hashimoto Y, Honda O, Oka S, Sasaki M, Daibo M, Honmou O. Cerebral aneurysm neck diameter is an independent predictor of progressive occlusion after stent-assisted coiling. Acta Neurochir (Wien). 2017 Jul;159(7):1313-1319.
  • Nakamura H, Sasaki Y, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Namioka T, Namioka A, Onodera R, Suzuki J, Nagahama H, Mikami T, Wanibuchi M, Kocsis JD, Honmou O. Elevated brain derived neurotrophic factor (BDNF) levels in plasma but not serum reflect in vivo functional viability of infused mesenchymal stem cells after middle cerebral artery occlusion in rat. J Neurosurg Sci. 2017 Feb 8.
  • Noshiro S, Mikami T, Kataoka-Sasaki Y, Sasaki M, Ohnishi H, Ohtaki S, Wanibuchi M, Mikuni N, Kocsis JD, Honmou O. Co-expression of tissue factor and IL-6 in immature endothelial cells of cerebral cavernous malformations. J Clin Neurosci. 2017 Mar;37:83-90.
  • Wanibuchi M, Kataoka-Sasaki Y, Sasaki M, Oka S, Otsuka Y, Yamaguchi M, Ohnishi H, Ohtaki S, Noshiro S, Ookawa S, Mikami T, Mikuni N, Honmou O. Interleukin-13 receptor alpha 2 as a marker of poorer prognosis in high-grade astrocytomas. J Neurosurg Sci. 2018 Jun;62(3):239-244.
  • Nakazaki M, Sasaki M, Kataoka-Sasaki Y, Oka S, Namioka T, Namioka A, Onodera R, Suzuki J, Sasaki Y, Nagahama H, Mikami T, Wanibuchi M, Kocsis JD, Honmou O. Intravenous infusion of mesenchymal stem cells inhibits intracranial hemorrhage after recombinant tissue plasminogen activator therapy for transient middle cerebral artery occlusion in rats. J Neurosurg. 2017 Oct;127(4):917-926.
  • Morita T, Sasaki M, Kataoka-Sasaki Y, Nakazaki M, Nagahama H, Oka S, Oshigiri T, Takebayashi T, Yamashita T, Kocsis JD, Honmou O. Intravenous infusion of mesenchymal stem cells promotes functional recovery in a model of chronic spinal cord injury. Neuroscience. 2016 Aug 30. [Epub ahead of print]
  • Noshiro S, Mikami T, Kataoka-Sasaki Y, Sasaki M, Hashi K, Ohtaki S, Wanibuchi M, Mikuni N, Kocsis JD, Honmou O., Biological relevance of tissue factor and IL-6 in arteriovenous malformations. Neurosurg Rev. 2016 Aug 19. [Epub ahead of print]
  • Sasaki Y, Sasaki M, Kataoka-Sasaki Y, Nakazaki M, Nagahama H, Suzuki J, Tateyama D, Oka S, Namioka T, Namioka A, Onodera R, Mikami T, Wanibuchi M, Kakizawa M, Ishiai S, Kocsis JD, Honmou O. Synergic Effects of Rehabilitation and Intravenous Infusion of Mesenchymal Stem Cells After Stroke in Rats. Phys Ther. 2016 May 12. [Epub ahead of print]
  • Nakazaki M, Nonaka T, Takahashi A, Yonemasu Y, Nomura T, Onda T, Honda O, Hashimoto Y, Ohnishi H, Sasaki M, Daibo M, Honmou O. Double balloon protection during carotid artery stenting for vulnerable carotid stenosis reduces the incidence of new brain lesions. Acta Neurochir (Wien). 2016 May 2. [Epub ahead of print]
  • Ohtaki S, Wanibuchi M, Kataoka-Sasaki Y, Sasaki M, Oka S, Noshiro S, Akiyama Y, Mikami T, Mikuni N, Kocsis JD, Honmou O. ACTC1 as an invasion and prognosis marker in glioma. J Neurosurg. 2016 Apr 15:1-9. [Epub ahead of print]
  • Takayanagi A, Sasaki M, Kataoka-Sasaki Y, Kobayashi K, Matsuda Y, Oka S, Masumori N, Kocsis JD, Honmou O. Intravenous Preload of Mesenchymal Stem Cells Rescues Erectile Function in a Rat Model of Cavernous Nerve Injury. J Sex Med. 12 (2015): 713-21.
  • Matsushita T, Lankford KL, Arroyo EJ, Sasaki M, Neyazi M, Radtke C, Kocsis JD. Diffuse and persistent blood-spinal cord barrier disruption after contusive spinal cord injury rapidly recovers following intravenous infusion of bone marrow mesenchymal stem cells. Exp Neurol. 267 (2015) :152-64.
  • Suzuki S, Kawamata J, Iwahara N, Matsumura A, Hisahara S, Matsushita T, Sasaki M, Honmou O, Shimohama S. Intravenous mesenchymal stem cell administration exhibits therapeutic effects against 6-hydroxydopamine-induced dopaminergic neurodegeneration and glial activation in rats. Neurosci Lett. 2015 Jan 1;584:276-81.
  • Lankford KL, Brown RJ, Sasaki M, Kocsis JD. Olfactory ensheathing cells, but not Schwann cells, proliferate and migrate extensively within moderately X-irradiated juvenile rat brain. Glia. 62 (2014) : 52-63.
  • Suzuki J, Sasaki M, Harada K, Bando M, Kataoka Y, Onodera R, Mikami T, Wanibuchi M, Mikuni N, Kocsis JD, Honmou O. Bilateral Cortical Hyperactivity Detected by fMRI Associates with Improved Motor Function Following Intravenous Infusion of Mesenchymal Stem Cells in a Rat Stroke Model, Brain Research 1497 (2013) 15-22
  • Kocsis JD, Honmou O. Bone marrow stem cells in experimental stroke. Prog Brain Res. 2012;201:79-98. doi: 10.1016/B978-0-444-59544-7.00005-6.
  • Inden M, Takata K, Nishimura K, Kitamura Y, Ashihara E, Yoshimoto K, Ariga H, Honmou O, Shimohama S. Therapeutic effects of human mesenchymal and hematopoietic stem cells on rotenone-treated parkinsonian mice. J Neurosci Res. 2013 Jan;91(1):62-72. doi: 10.1002/jnr.23128. Epub 2012 Oct 17. PMID: 23073839 [PubMed - in process]
  • Honmou O, Onodera R, Sasaki M, Waxman SG, Kocsis JD. Mesenchymal stem cells:therapeutic outlook for stroke. Trends Mol Med. 2012 Mar 27. [Epub ahead of print] PubMed PMID: 22459358.
  • Sasaki Y, Honmou O. [Bone marrow stem cell therapy for stroke]. Nihon Rinsho. 2011 Dec;69(12):2203-8. Japanese. PubMed PMID: 22242320.
  • Radtke C, Sasaki M, Lankford KL, Gallo V, Kocsis JD. CNPase expression in olfactory ensheathing cells. J Biomed Biotechnol. 2011;2011:608496. Epub 2011 Nov 16. PubMed PMID: 22174557; PubMed Central PMCID: PMC3228405.
  • Katada R, Nishitani Y, Honmou O, Mizuo K, Okazaki S, Tateda K, Watanabe S, Matsumoto H. Expression of aquaporin-4 augments cytotoxic brain edema after traumatic brain injury during acute ethanol exposure. Am J Pathol. 2012 Jan;180(1):17-23. Epub 2011 Nov 1. PubMed PMID: 22051773.
  • Sasaki M, Honmou O, Radtke C, Kocsis JD. Development of a middle cerebral artery occlusion model in the nonhuman primate and a safety study of i.v. infusion of human mesenchymal stem cells. PLoS One. 2011;6(10):e26577. Epub 2011 Oct 24. PubMed PMID: 22039510; PubMed Central PMCID: PMC3200343.
  • Song CH, Honmou O, Furuoka H, Horiuchi M. Identification of chemoattractive factors involved in the migration of bone marrow-derived mesenchymal stem cells to brain lesions caused by prions. J Virol. 2011 Nov;85(21):11069-78. Epub 2011 Aug 3. PubMed PMID: 21813601; PubMed Central PMCID: PMC3194951.
  • Matsushita T, Kibayashi T, Katayama T, Yamashita Y, Suzuki S, Kawamata J, Honmou O, Minami M, Shimohama S. Mesenchymal stem cells transmigrate across brain microvascular endothelial cell monolayers through transiently formed inter-endothelial gaps. Neurosci Lett. 2011 Sep 8;502(1):41-5. Epub 2011 Jul 20. PubMed PMID: 21798315.
  • Honmou O, Houkin K, Matsunaga T, Niitsu Y, Ishiai S, Onodera R, Waxman SG, Kocsis JD. Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke. Brain. 2011 Jun;134(Pt 6):1790-807. Epub 2011 Apr 14. PubMed PMID: 21493695; PubMed Central PMCID: PMC3102237.
  • Sasaki M, Lankford KL, Radtke C, Honmou O, Kocsis JD. Remyelination after olfactory ensheathing cell transplantation into diverse demyelinating environments. Exp Neurol. 2011 May;229(1):88-98. Epub 2011 Jan 28. Review. PubMed PMID: 21281634.
  • Sasaki M, Lankford KL, Brown RJ, Ruddle NH, Kocsis JD. Focal experimental autoimmune encephalomyelitis in the Lewis rat induced by immunization with myelin oligodendrocyte glycoprotein and intraspinal injection of vascular endothelial growth factor. Glia. 2010 Oct;58(13):1523-31. PubMed PMID: 20645414.
  • Honmou O, Houkin K. [Stem cell therapy for cerebral ischemia]. No Shinkei Geka. 2010 Jun;38(6):515-20. Review. Japanese. PubMed PMID: 20543224.
  • Onodera R, Teramukai S, Tanaka S, Kojima S, Horie T, Matoba S, Murohara T, Matsubara H, Fukushima M; BMMNC Follow-Up Study Investigators; M-PBMNC Follow-Up Study Investigators. Bone marrow mononuclear cells versus G-CSF-mobilized peripheral blood mononuclear cells for treatment of lower limb ASO: pooled analysis for long-term prognosis. Bone Marrow Transplant. 2011 Feb;46(2):278-84. Epub 2010 May 17. PubMed PMID: 20479708.
  • Osaka M, Honmou O, Murakami T, Nonaka T, Houkin K, Hamada H, Kocsis JD. Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome. Brain Res. 2010 Jul 9;1343:226-35. Epub 2010 May 12. PubMed PMID: 20470759.
  • Komatsu K, Honmou O, Suzuki J, Houkin K, Hamada H, Kocsis JD. Therapeutic time window of mesenchymal stem cells derived from bone marrow after cerebral ischemia. Brain Res. 2010 Jun 2;1334:84-92. Epub 2010 Apr 9. PubMed PMID: 20382136.
  • Kataoka Y, Kalanithi PS, Grantz H, Schwartz ML, Saper C, Leckman JF, Vaccarino FM. Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. J Comp Neurol. 2010 Feb 1;518(3):277-91. PubMed PMID: 19941350; PubMed Central PMCID: PMC2846837.
  • Sasaki M, Radtke C, Tan AM, Zhao P, Hamada H, Houkin K, Honmou O, Kocsis JD. BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury. J Neurosci. 2009 Nov 25;29(47):14932-41. PubMed PMID: 19940189; PubMed Central PMCID: PMC2825276.
  • Zheng W, Honmou O, Miyata K, Harada K, Suzuki J, Liu H, Houkin K, Hamada H, Kocsis JD. Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia. Brain Res. 2010 Jan 15;1310:8-16. Epub 2009 Nov 12. PubMed PMID: 19913518.
  • Markakis EA, Sasaki M, Lankford KL, Kocsis JD. Convergence of cells from the progenitor fraction of adult olfactory bulb tissue to remyelinating glia in demyelinating spinal cord lesions. PLoS One. 2009 Sep 29;4(9):e7260. PubMed PMID: 19787061; PubMed Central PMCID: PMC2747269.
  • Horie T, Onodera R, Akamastu M, Ichikawa Y, Hoshino J, Kaneko E, Iwashita C, Ishida A, Tsukamoto T, Teramukai S, Fukushima M, Kawamura A; Japan Study Group of Peripheral Vascular Regeneration Cell Therapy (JPRCT). Long-term clinical outcomes for patients with lower limb ischemia implanted with G-CSF-mobilized autologous peripheral blood mononuclear cells. Atherosclerosis. 2010 Feb;208(2):461-6. Epub 2009 Aug 3. PubMed PMID: 19720375.
  • Kawamoto A, Katayama M, Handa N, Kinoshita M, Takano H, Horii M, Sadamoto K, Yokoyama A, Yamanaka T, Onodera R, Kuroda A, Baba R, Kaneko Y, Tsukie T, Kurimoto Y, Okada Y, Kihara Y, Morioka S, Fukushima M, Asahara T. Intramuscular transplantation of G-CSF-mobilized CD34(+) cells in patients with critical limb ischemia: a phase I/IIa, multicenter, single-blinded, dose-escalation clinical trial. Stem Cells. 2009 Nov;27(11):2857-64. PubMed PMID: 19711453.
  • Katada R, Nishitani Y, Honmou O, Okazaki S, Houkin K, Matsumoto H. Prior ethanol injection promotes brain edema after traumatic brain injury. J Neurotrauma. 2009 Nov;26(11):2015-25. PubMed PMID: 19558208.
  • Kocsis JD, Lankford KL, Sasaki M, Radtke C. Unique in vivo properties of olfactory ensheathing cells that may contribute to neural repair and protection following spinal cord injury. Neurosci Lett. 2009 Jun 12;456(3):137-42. Epub 2009 Jan 17. Review. PubMed PMID: 19429149; PubMed Central PMCID: PMC2713444.
  • Sasaki M, Honmou O, Kocsis JD. A rat middle cerebral artery occlusion model and intravenous cellular delivery. Methods Mol Biol. 2009;549:187-95. PubMed PMID: 19378204.
  • Song CH, Honmou O, Ohsawa N, Nakamura K, Hamada H, Furuoka H, Hasebe R, Horiuchi M. Effect of transplantation of bone marrow-derived mesenchymal stem cells on mice infected with prions. J Virol. 2009 Jun;83(11):5918-27. Epub 2009 Mar 18. PubMed PMID: 19297502; PubMed Central PMCID: PMC2681942.
  • Liu H, Koyanagi I, Chiba H, Wanibuchi M, Honmou O, Yamaki T, Houkin K. Spinal cord infarct as the initial clinical presentation of intravascular malignant lymphomatosis. J Clin Neurosci. 2009 Apr;16(4):570-3. Epub 2009 Feb 5. PubMed PMID: 19200739.
  • Toyama K, Honmou O, Harada K, Suzuki J, Houkin K, Hamada H, Kocsis JD. Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia. Exp Neurol. 2009 Mar;216(1):47-55. Epub 2008 Nov 27. PubMed PMID: 19094989.
  • Matoba S, Tatsumi T, Murohara T, Imaizumi T, Katsuda Y, Ito M, Saito Y, Uemura S, Suzuki H, Fukumoto S, Yamamoto Y, Onodera R, Teramukai S, Fukushima M, Matsubara H; TACT Follow-up Study Investigators. Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells (Therapeutic Angiogenesis by Cell Transplantation [TACT] trial) in patients with chronic limb ischemia. Am Heart J. 2008 Nov;156(5):1010-8. Epub 2008 Sep 19. PubMed PMID: 19061721.
  • Omori Y, Honmou O, Harada K, Suzuki J, Houkin K, Kocsis JD. Optimization of a therapeutic protocol for intravenous injection of human mesenchymal stem cells after cerebral ischemia in adult rats. Brain Res. 2008 Oct 21;1236:30-8. Epub 2008 Aug 9. PubMed PMID: 18722359; PubMed Central PMCID: PMC2605387.
  • Radtke C, Sasaki M, Lankford KL, Vogt PM, Kocsis JD. Potential of olfactory ensheathing cells for cell-based therapy in spinal cord injury. J Rehabil Res Dev. 2008;45(1):141-51. Review. PubMed PMID: 18566933.
  • Lankford KL, Sasaki M, Radtke C, Kocsis JD. Olfactory ensheathing cells exhibit unique migratory, phagocytic, and myelinating properties in the X-irradiated spinal cord not shared by Schwann cells. Glia. 2008 Nov 15;56(15):1664-78. PubMed PMID: 18551623.
  • Saito F, Nakatani T, Iwase M, Maeda Y, Hirakawa A, Murao Y, Suzuki Y, Onodera R, Fukushima M, Ide C. Spinal cord injury treatment with intrathecal autologous bone marrow stromal cell transplantation: the first clinical trial case report. J Trauma. 2008 Jan;64(1):53-9. PubMed PMID: 18188099.
  • Marui A, Tabata Y, Kojima S, Yamamoto M, Tambara K, Nishina T, Saji Y, Inui K, Hashida T, Yokoyama S, Onodera R, Ikeda T, Fukushima M, Komeda M. A novel approach to therapeutic angiogenesis for patients with critical limb ischemia by sustained release of basic fibroblast growth factor using biodegradable gelatin hydrogel: an initial report of the phase I-IIa study. Circ J. 2007 Aug;71(8):1181-6. PubMed PMID: 17652878.
  • Onda T, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD. Therapeutic benefits by human mesenchymal stem cells (hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia. J Cereb Blood Flow Metab. 2008 Feb;28(2):329-40. Epub 2007 Jul 18. PubMed PMID: 17637706; PubMed Central PMCID: PMC2605394.
  • Sasaki M, Li B, Lankford KL, Radtke C, Kocsis JD. Remyelination of the injured spinal cord. Prog Brain Res. 2007;161:419-33. Review. PubMed PMID: 17618995; PubMed Central PMCID: PMC2605400.
  • Honmou O, Houkin K. [A cell therapy for stroke]. Nihon Rinsho. 2006 Oct 28;64 Suppl 7:664-6. Review. Japanese. PubMed PMID: 17461219.
  • Radtke C, Spies M, Sasaki M, Vogt PM, Kocsis JD. Demyelinating diseases and potential repair strategies. Int J Dev Neurosci. 2007 May;25(3):149-53. Epub 2007 Mar 3. Review. PubMed PMID: 17408905; PubMed Central PMCID: PMC2692731.
  • Ukai R, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD. Mesenchymal stem cells derived from peripheral blood protects against ischemia. J Neurotrauma. 2007 Mar;24(3):508-20. PubMed PMID: 17402856; PubMed Central PMCID: PMC2605398.
  • Harada K, Honmou O, Liu H, Bando M, Houkin K, Kocsis JD. Magnetic resonance lactate and lipid signals in rat brain after middle cerebral artery occlusion model. Brain Res. 2007 Feb 23;1134(1):206-13. Epub 2006 Dec 29. PubMed PMID: 17196558; PubMed Central PMCID: PMC2605392.
  • Harada K, Honmou O, Odawara Y, Bando M, Houkin K. Optimization of three-dimensional time-of-flight magnetic resonance angiography of the intracranial arteries. Neurol Med Chir (Tokyo). 2006 Nov;46(11):523-8; discussion 528. PubMed PMID: 17124366.
  • Dombrowski MA, Sasaki M, Lankford KL, Kocsis JD, Radtke C. Myelination and nodal formation of regenerated peripheral nerve fibers following transplantation of acutely prepared olfactory ensheathing cells. Brain Res. 2006 Dec 13;1125(1):1-8. Epub 2006 Nov 16. PubMed PMID: 17112480; PubMed Central PMCID: PMC2673087.
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